Abstract:

Background and Aim: Consumption of omega-3 fatty acids can alter the fertility and metabolic syndrome in polycystic ovarian syndrome, which may enhance the benefits of training. The aim of this study was to investigate the effect of 8 weeks resistance training and omega3 supplementation on anti-mullerian hormone level and cardiometabolic parameters in women with polycystic ovarian syndrome.

Materials and Methods: In this semi-experimental study with pretest-posttest design, thirty PCOS patients (age: 28.16±4.29 y, body mass index: 25.31±1.47 kg/m²) were randomly assigned to resistance training (n=10), omega-3 supplementation plus resistance training (n=10) or control (n=10) groups. Resistance training program was performed 50-60 min/d, 3d/wk, for 8 weeks. Serum levels of anti-mullerian hormone, body composition and metabolic parameters were assessed before and after the training period. Data was analyzed using t-test and analysis of variance.

Results: After an 8 weeks resistance training total cholesterol, LDL-cholesterol, triglycerides and insulin resistance index were significantly decreased (p<0.05). Data analysis showed that omega-3 supplementation in conjunction with resistance training lead to greater improvement in metabolic indices and anti-mullerian hormone level (p<0.05).

‍Conclusion: These results suggest that resistance training and omega-3 supplementation can have beneficial effects on ovarian function and metabolic indices over a two-month period. Based on the results of this study, a daily consumption of omega-3 and resistance training is suggested for patients with polycystic ovary syndrome.