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pajoohande 2009, 14(1): 37-42 Back to browse issues page
A Comparing Study of Clarithromycin XL and Co-amoxiclav for Treatment of Chronic Sinusitis
Amini M *, Yarmohammadi ME
, mamini55602@yahoo.com
Abstract:   (12270 Views)
Background and Aim: chronic sinusitis is one of the most common medical problems and affected annually 30 million people in USA. This study the efficacy and safety of clarithromycin XL and Co-amoxiclove on clinical and CT scan finding in patients suffering from chronic sinusitis were compared. Material and methods: In this clinical trial a total of 59 subjects (62.7% male, 37.3% female, mean age 28 years) with clinical symptoms and CT scan findings of chronic sinusitis were divided into two groups and treated with clarithromycin XL or Co-amoxiclav. Results: clinical success rates at the end of therapy similar in two groups, but in subjects treated with clarithromycin XL, CT scan findings had a better results than Co-amoxiclav group (53% versus 29%). Gastrointestinal discomfort was the most frequent treatment–related adverse effects, but no significant difference in two groups. Conclusion: Results demonstrated that clinical success rate of clarithromycin XL and Co-amoxiclav, was similar for treatment of chronic sinusitis, but clarithromycin XL was more effective in improvement of CT scan findings.
Keywords: Chronic Sinusitis, Chronic Rhinosinusitis, Clarithromycin, Co-amoxiclav
Full-Text [PDF 199 kb]   (6943 Downloads)    
Type of Study: Original | Subject: Medicine
Received: 2017 | Accepted: 2017 | Published: 2017
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Amini M, Yarmohammadi ME. A Comparing Study of Clarithromycin XL and Co-amoxiclav for Treatment of Chronic Sinusitis. pajoohande. 2009; 14 (1) :37-42
URL: http://pajoohande.sbmu.ac.ir/article-1-747-en.html


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