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Low HDL prevalence in patients with acute coronary syndrome admitted in Loghman Hakim hospital
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Maryam Taherkhani *   , Hamed Asadi , Adineh Taherkhani |
| , m.taherkhani@sbmu.ac.ir |
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Abstract: (7618 Views) |
| Abstract: Background and Aim: Cardiovascular disorders especially coronary artery diseases are the most common causes of death in the developed and developing countries. According to large studies low HDL is an independent predictor of coronary artery diseases. Its cost effective to treat low HDL compare with coronary diseases. The aim of this study is determining the prevalence and causes of low HDL in patients with acute coronary syndrome. Materials and Methods: This was a cross sectional study. 300 patients who admitted in CCU of Loghman Hakim hospital because of acute coronary syndrome enrolled in our study. These parameters surveyed in this study: plasma level of total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, age, sex, history of HTN, DM, IHD, CVA, renal and hepatic disease. The information was analyzed with chi-square test and t-test. Results: HDL average in women was 50 mg/dl and in men was 48 mg/dl. TG average in men was 180 mg/dl and in women was 183 mg/dl and cholesterol average in men was 196 mg/dl and in women was 182 mg/dl. Thus, there was not a significant association between two sexes. There were no patients with HDL lower than 25 mg/dl. 80 patients (26.7%) had HDL lower than 40 mg/dl and 54 patients (18%) had HDL more than 60 mg/dl. In 1% of patients low HDL was the unique risk factor of IHD. Between hypercholesterolemia and low HDL with p-value of <0.03 and between high LDL and low HDL with p-value of <0.05 were significant association. There was no significant association between low HDL in patients with and without HTN and patients with and without DM. There was significant association between smoking and low HDL (p-value<0.024). Total cholesterol/HDL index in all patients was 4 over 1. DM, HTN and smoking have no significant effect on this index. Low HDL was the most important factor that affects this index and there was significant association between low HDL and total cholesterol/HDL index (P<0.05). Conclusion: About one third of patients who was admitted with acute coronary syndrome had HDL less than 40 mg/dl. Although determining independent role of low HDL in our study was not possible but it needs more concern. |
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| Keywords: HDL, Ischemic heart disease, Dyslipidemia |
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Full-Text [PDF 202 kb]
(2328 Downloads)
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Type of Study: Original |
Subject:
Medicine
Received: 2017 | Accepted: 2017 | Published: 2017
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