[Home ] [Archive]    
:: Volume 16, Issue 3 (July& August 2011 2011) ::
pajoohande 2011, 16(3): 144-146 Back to browse issues page
Congenital hypomyelinating neuropathy in a newborn: a case report
Mohammad Barzegar *, Majid Mahallei, Mohammad Bagher Hosseini
Professor, Pediatric Neurology Department, Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran , mm_barzegar@yahoo.com
Abstract:   (8932 Views)
Congenital hypomyelinating neuropathy (CHN) is a rare severe polyneuropathy of neonates presenting with hypotonia, areflexia and severe muscular weakness leading to early mortality or profound morbidity. Here, we report a case of this disease presenting at birth with severe hypotonia, weak respiratory effort and ventilator dependency. Electrodiagnostic study showed severe nerve conduction velocity delay sural nerve biopsy demonstrated nerve bandles without any myelin. These finding are compatible with congenital hypomyelinating neuropathy. Thus, CHN should be considered in differential diagnosis of severe neonatal hypotonia.
Keywords: Congenital Neuropathy, Hypomyelination, Hypotonia, Infant, Newborn
Full-Text [PDF 78 kb]   (2808 Downloads)    
Type of Study: Original | Subject: Medicine
Received: 2017 | Accepted: 2017 | Published: 2017
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mohammad Barzegar, Majid Mahallei, Mohammad Bagher Hosseini. Congenital hypomyelinating neuropathy in a newborn: a case report. pajoohande. 2011; 16 (3) :144-146
URL: http://pajoohande.sbmu.ac.ir/article-1-1163-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 16, Issue 3 (July& August 2011 2011) Back to browse issues page
Persian site map - English site map - Created in 0.06 seconds with 30 queries by YEKTAWEB 4419