[Home ] [Archive]    
:: Volume 14, Issue 4 (october & november 2009) ::
pajoohande 2009, 14(4): 211-214 Back to browse issues page
Procalcitonin as a marker of bacterial infection in febrile neutropenic children
Aliasghar Halimiasl *, Kiomars Pourrostami, Ali Faraji, Saeed Yaasoubi, Farideh Mousavi, Naser Valaie, Naser Valaie, Mardavigh Alebouyeh
, aliasgharhalimiasl@yahoo.com
Abstract:   (12678 Views)
Background and Aim: Since neutropenic patients with malignancies are at high risk of contracting life-threatening infections, reliable and readily available parameters to diagnosis or rule out infection are of utmost importance. The objective of the present study was to determine the accuracy of procalcitonin (PCT) compared with culture to predict bacterial infection in children with febrile neutropenia. Materials and Methods: Blood culture and serum procalcitonin level were investigated in all studied febrile neutropenic children. Bacterial infection was defined as children with positive blood cultures or serum procalcitonin level of >0.5ng/ml. Results: The study population included 29 boys and 22 girls with the mean age (±standard deviation) of 6±3.5 years. PCT differed significantly between bacterimic and non-bacterimic episodes for the prediction of bacterimic patients. The associated positive predictive value (PPV) and negative predictive value (NPV) of procalcitonin test (in diagnosis of bacterial infection) were 50% and 97/4%, respectively. Conclusions: A rapid determination of procalcitonin concentration could be useful for early diagnosis of children with febrile neutropenia since the test showed an acceptable NPV.
Keywords: Neutropenia, Malignancy, Procalcition, Bacterial infection.
Full-Text [PDF 101 kb]   (2883 Downloads)    
Type of Study: Original | Subject: Medicine
Received: 2017 | Accepted: 2017 | Published: 2017
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aliasghar Halimiasl, Kiomars Pourrostami, Ali Faraji, Saeed Yaasoubi, Farideh Mousavi, Naser Valaie, et al . Procalcitonin as a marker of bacterial infection in febrile neutropenic children. pajoohande. 2009; 14 (4) :211-214
URL: http://pajoohande.sbmu.ac.ir/article-1-809-en.html


Volume 14, Issue 4 (october & november 2009) Back to browse issues page
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4071