|
Comparison of Irritable Bowel Syndrome (IBS) in Gastro Esophageal Reflux Disease (GERD) Patients with and without Esophagitis
|
Nikpoor Sh *   , Vahedi E |
|
|
|
Abstract: (12385 Views) |
| Background: Considering the prevalence of Gastro Esophageal Reflux Disease (GERD) and Irritable bowel syndrome (IBS) and based on recent reports which corresponded a high overlapping between these disorders, and also division of GERD into two groups with Esophagitis (ERD) and without Esophagitis (NERD), this study was performed in order to compare the prevalence of IBS among both ERD and NERD cases, referring to GI clinic of Loghman haspital in 2005. Materials and Methods: this cross sectional analytic study, was performed on 160 patients with clinical diagnosis of GERD referring to GI clinic. These patients were divided, according to endoscopic findings, into two groups of ERD and NERD each contained 80. Sampling method was simple random. patients with IBS were identified based on questionnaire of Rome (II) criteria. Data were analysed using statistic program of spss-v.12. P-value of less than 0.05 was considered statistically significant. Results: prevalence of IBS in GERD was found to be 15% [in ERD 7.5% and in NERD 22.5%] (p=0.008). Prevalence of GERD in patients <45 years old (50.6%) was equivalent to that of patients > 45 (49/4%). 23.3% of GERD cases older than 65years had NERD, whereas 76.7% of them had ERD. The most provalent association between IBS and GERD (45.8%) [ERD (50%) and NERD (44.5%)] was in ages between 45-54 years. There were no IBS cases in ages between 35 and 44, nor in above 65 years old. The prevalence of GERD revealed to be 54% and 46% in females and males, respectively. Applying the statistic tests, there was no significant difference (p>0.05). The prevalence of IBS in females with GERD was 1.7 times more than that of males. The prevalence of constipation-dominant pattern in IBS was 79% in GERD [83% in ERD and 78% in NERD] without any significant difference between ERD and NERD groups (p>0.05). Conclusion: Compared to ERD cases, the predominant association of IBS in NERD patients would suggest a probable common ethiologic or pathologic back ground between these two latter disorders. |
|
| Keywords: Gastro Esophageal Reflux Disease (GERD), Irritable Bowel Syndrome (IBS), Esophagitis. |
|
|
Full-Text [PDF 190 kb]
(3824 Downloads)
|
Type of Study: Original |
Subject:
Medicine
Received: 2017 | Accepted: 2017 | Published: 2017
|
|
|
|
|
|
|
| Add your comments about this article |
|
|
|
