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Efficacy of Photodynamic Therapy in Basal Cell Carcinoma
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Zohreh Tehranchinia *   , Hoda Rahimi , Ali Farnaghi |
| , zohreh_tehranchi@yahoo.com |
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Abstract: (10772 Views) |
| Background and Aim: Basal cell carcinoma (BCC) is the most common skin cancer. Photodynamic therapy (PDT), as a novel, non-invasive therapeutic approach, may be considered a valuable strategy. This study was designed to evaluate the efficacy of PDT in treatment of BCC. Materials and Methods: This clinical trial was achieved on 28 BCCs from 12 patients. Patients were treated with PDT monthly for 1-6 sessions and evaluated for clinical response, cosmetic results and probable side effects. Results: The study was achieved on 28 lesions from 12 patients. Complete response was achieved in 9 (32.1%) lesions (p<0.05). Patients who were younger (p<0.01) and those with smaller lesions (p<0.001) showed more complete response. Superficial BCC had also significant higher complete response rate (p<0.01). Complete response rate was lower in patients with positive history of radiotherapy for tinea capitis in childhood (p<0.05). Conclusion: PDT would be a good therapeutic approach in patients with BCC, especially superficial type. It is associated with high efficacy rate and low side effect. |
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| Keywords: Basal cell carcinoma, Photodynamic therapy, Photo chemotherapy |
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Full-Text [PDF 184 kb]
(2499 Downloads)
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Type of Study: Original |
Subject:
Medicine
Received: 2017 | Accepted: 2017 | Published: 2017
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