Background: The benefits of breastfeeding for both the infant and the mother are indisputable and the necessity of contraception during breast feeding is one of the most important issues in this regard. This study was conducted to evaluate the usage of minipill (progesterone only pills), its related problems, reasons for give it up and other factors. Materials and Methods: In this cross-sectional study, the contraception method, duration of minipill consumption, side effects and reasons for discontinuation were evaluated. Results: The mean age of participants was 24.8±5.3 years old and mean number of their children was 2.2±0.8. 47% used the minipill and 41.8% gave it up during an 18-month follow up. Side effects of minipill were as follow: 71.4% bleeding disturbances, 52.3% menstrual retard, 38% vaginal discharge, 28.5% spotting, 23.8% headache and palpitation, 4.76% dwindling flow of excreted milk and mastalgia. Conclusion: The usage of minipill is lower than what we expect which is of great concern. Moreover, the side effects and other related problems, are important issues that should be rigorously investigated.